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NVR 3-778 is a first-in-class, orally bioavailable hepatitis B virus (HBV) capsid assembly modulator (CAM) of the sulfamoylbenzamide chemical class used in research to inhibit HBV replication and the generation of infectious viral particles. It has been characterized in preclinical and clinical studies and is supplied for research use with high reported purity and defined physicochemical properties.
First-in-class capsid assembly modulator with demonstrated antiviral activity.
Orally bioavailable small molecule suitable for preclinical assays.
Pan-genotypic inhibition of HBV replication in cell-based models.
Solid, white to off-white material with reported solubility in DMSO and ethanol.
High reported purity appropriate for research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
VLX600 is a small-molecule oxidative phosphorylation (OxPhos) inhibitor and iron chelator used in cancer and mitochondrial metabolism research. It impairs mitochondrial respiration, induces autophagy, and shows selective cytotoxicity in quiescent or nutrient-starved tumor cells. Molecular formula C17H15N7; molecular weight 317.35; CAS 327031-55-0.
Inhibits mitochondrial oxidative phosphorylation.
Functions as an iron chelator.
Induces autophagy and promotes tumor cell death under nutrient limitation.
Useful as a reference compound for cancer metabolism studies.
Crystalline solid with reported DMSO solubility around 25 mg/mL.
Recommended storage at -20°C as a powder.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide is a small-molecule N-myristoyltransferase (NMT) inhibitor with potent enzymatic and cellular activity against Trypanosoma brucei. It demonstrates nanomolar potency and is supplied in solid and DMSO solution formulations for research use.